Clinical features of anti-mGluR5 encephalitis and comparison according to MRI positivity: a systematic review and analysis - Takeaways - MDSpire

Clinical features of anti-mGluR5 encephalitis and comparison according to MRI positivity: a systematic review and analysis

  • By

  • Jihong Han

  • Xiaofang Zhong

  • Lei Liu

  • Ruxu Zhang

  • Zhongyang Hu

  • June 5, 2026

  • 0 min

Share

  • 1

    Anti-mGluR5 encephalitis is a rare autoimmune neurological disorder characterized by diverse clinical manifestations.

  • 2

    Cognitive deficits, mood disturbances, and seizures are common symptoms among patients with anti-mGluR5 encephalitis.

  • 3

    MRI abnormalities were found in 52.5% of patients, but no significant correlation was observed with clinical outcomes.

  • 4

    Serum positivity for anti-mGluR5 antibodies is significantly higher than cerebrospinal fluid positivity.

  • 5

    Chinese patients with anti-mGluR5 encephalitis show a lower association with tumors compared to Western patients.

Original Source(s)

Clinical features of anti-mGluR5 encephalitis and comparison according to MRI positivity: a systematic review and analysis

  • by Jihong Han, Xiaofang Zhong, Lei Liu, Ruxu Zhang, Zhongyang Hu

  • June 5, 2026

Related Content

Baptist Health Foundation Receives $2M Gift to Establish Endowed Chair at Baptist Health Miami Neuroscience Institute

Baptist Health Foundation announced that it has received a $2 million donation from Anthony and Joyce Esernia to establish a new endowed chair at Baptist Health Miami Neuroscience Institute.

  • May 1, 2026

  • 5 min
UCI Health earns NAEC Level 4 Epilepsy Center certification

UCI Health has been awarded National Association of Epilepsy Centers certification as a Level 4 Epilepsy Center.

  • May 14, 2026

  • 1 min
This Week’s CGT News: Novo’s Parkinson’s Pivot

Novo Nordisk’s Parkinson’s cell therapy finds a new home at Cellular Intelligence, while base editing, prime editing, and large-insertion genome writing push forward

  • May 18, 2026

  • 7 min