24-hour diastolic blood pressure average real variability predicts renal progression in diabetic kidney disease: a comprehensive cohort study - Takeaways - MDSpire

24-hour diastolic blood pressure average real variability predicts renal progression in diabetic kidney disease: a comprehensive cohort study

  • By

  • Yanqing Hu

  • Shan Ma

  • Ting Yu

  • Dan Wu

  • Yang Wu

  • April 20, 2026

  • 0 min

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  • 1

    Diastolic blood pressure variability (DBPV) is a significant predictor of renal progression in diabetic kidney disease (DKD).

  • 2

    A 1 mmHg increase in 24-hour DBP average real variability (ARV) correlates with an 18% higher risk of rapid eGFR decline.

  • 3

    The optimal threshold for 24-hour DBP ARV predicting ESRD is 10.2 mmHg, increasing ESRD risk by 3.1-fold above this level.

  • 4

    Patients with rising DBPV over time face a 2.4-fold higher risk of ESRD compared to those with decreasing DBPV.

  • 5

    Calcium channel blockers (CCBs) are associated with lower DBP ARV compared to other antihypertensive medications in DKD patients.

Original Source(s)

24-hour diastolic blood pressure average real variability predicts renal progression in diabetic kidney disease: a comprehensive cohort study

  • by Yanqing Hu, Shan Ma, Ting Yu, Dan Wu, Yang Wu

  • April 20, 2026

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