AI may cut breast biopsy review time by 44%

A paired-reader study found that pathologists maintained high diagnostic agreement while reviewing breast biopsy slides faster with AI assistance.

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In the retrospective, single-center CASCADE study, 2 pathologists reviewed 194 breast biopsy cases using standard digital pathology and AI-assisted digital pathology.
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Mean review time decreased from 71.12 seconds with standard digital pathology to 40.18 seconds with AI assistance, a 44% reduction.
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Cancer diagnostic agreement was 97% with standard digital pathology and 99% with AI assistance; sensitivity was 98% and 100%, respectively.
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For DCIS, agreement increased from 93% to 99% and sensitivity from 86% to 100%, but the subgroup included only 21 positive cases.
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AI-guided IHC preordering was estimated to reduce turnaround time by about 2.5 days for applicable true-positive cases, but this modeled reduction requires prospective evaluation.

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