The correlation between the trajectory of plasma atherosclerosis-inducing index in the examination population and the risk of developing metabolic dysfunction-associated steatotic liver disease - Takeaways - MDSpire

The correlation between the trajectory of plasma atherosclerosis-inducing index in the examination population and the risk of developing metabolic dysfunction-associated steatotic liver disease

  • By

  • Yongxin Li

  • Changying Zhao

  • Jun Wang

  • Tao Shi

  • March 31, 2026

  • 0 min

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  • 1

    Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is increasingly prevalent, affecting up to 37% of adults globally.

  • 2

    The study identified three Atherogenic Index of Plasma (AIP) trajectory patterns: low-stable, moderate-stable, and high-stable.

  • 3

    Participants in the high-stable AIP group had a 2.23-fold increased risk of developing MASLD compared to the low-stable group.

  • 4

    The moderate-stable AIP group also showed an increased risk of MASLD, with a hazard ratio of 1.42.

  • 5

    Monitoring AIP trajectories may serve as a valuable tool for early identification and prevention of MASLD.

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