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1
Neuroglial cells, including microglia and astrocytes, are crucial regulators of immune processes in the central nervous system.
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2
Microglia act as resident macrophages, responding to injury and infection while regulating neural cell functions and inflammatory signaling.
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3
Astrocytes maintain the blood-brain barrier and respond to CNS injury through reactive astrogliosis, influencing inflammation.
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4
Oligodendrocyte precursor cells (OPCs) exhibit immune functions, including phagocytosis and cytokine release, impacting diseases like Multiple Sclerosis.
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The interplay between neuroglia and peripheral immune cells is vital for CNS homeostasis and could inform new therapeutic strategies.