Cultural bias in large language models’ ability to follow neuroradiology guidelines - Takeaways - MDSpire
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

Cultural Influences on the Compliance of Large Language Models with Neuroradiology Guidelines

  • By

  • Naël Bazerbachi

  • Raphaël Bentegeac

  • Giada Pistilli

  • Su-Hwan Kim

  • Philippe Amouyel

  • Jean-Pierre Pruvo

  • Lotfi Hacein-Bey

  • Aghiles Hamroun

  • Grégory Kuchcinski

  • Bastien Le Guellec

  • May 26, 2026

Share

  • 1

    Medical imaging complexity leads to clinician challenges in ordering appropriate studies and frequent over-utilization of imaging modalities.

  • 2

    A multi-country evaluation showed significant variations in guideline adherence, ranging from 58% to 86%, highlighting inconsistencies in neuroradiology.

  • 3

    Large language models (LLMs) have potential as decision-support tools in neuroradiology but exhibit biases, including demographic and geographic biases.

  • 4

    Geographic bias in LLMs may misalign clinical workflows with local practice standards, impacting integrated care pathways and treatment philosophies.

  • 5

    The study investigates whether LLMs disproportionately adhere to U.S. neuroradiology guidelines over international ones, using fictitious clinical vignettes.

Original Source(s)

Cultural bias in large language models’ ability to follow neuroradiology guidelines

  • by Naël Bazerbachi, Raphaël Bentegeac, Giada Pistilli, Su-Hwan Kim, Philippe Amouyel, Jean-Pierre Pruvo, Lotfi Hacein-Bey, Aghiles Hamroun, Grégory Kuchcinski, Bastien Le Guellec

  • May 26, 2026

Related Content

Clinical Characteristics and Endovascular Treatment Results of Spinal Arteriovenous Fistulas Arising from Internal Iliac Artery Branches

Mental Health Content Accuracy Varies

Researchers found misinformation rates ranged from 0% to 57% across platforms and topics, with higher rates reported in several TikTok studies compared with YouTube.

FDA Approves New Iohexol Vials

The approval includes additional 300 mg iodine/mL and 350 mg iodine/mL vial presentations.