Bibliometric Analysis of Global Research Trends in Spatially Fractionated Radiotherapy

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Spatially Fractionated Radiotherapy (SFRT) optimizes tumor ablation while preserving normal tissue integrity through dose redistribution.
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A bibliometric evaluation identified 427 eligible publications on SFRT from 2005 to 2025, highlighting significant research growth.
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The United States leads in cumulative research output on SFRT, while France shows notable institutional productivity and citation impact.
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Research themes in SFRT have evolved from microbeam technology to advancements in proton minibeam therapy and clinical feasibility.
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Future SFRT research should focus on biological markers, refining delivery technologies, and establishing standardized protocols.

Frontiers In Oncology

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