Case Report: Fibrin-associated large B-cell lymphoma developing within a cystic lesion of the adrenal gland: unexpected guest - Takeaways - MDSpire

Case Report: Fibrin-associated large B-cell lymphoma developing within a cystic lesion of the adrenal gland: unexpected guest

  • By

  • Haneen Al-Maghrabi

  • Bayan Ali Alghamdi

  • May 8, 2026

  • 0 min

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  • 1

    Fibrin-associated large B-cell lymphoma (FA-LBCL) is a rare EBV-positive malignancy classified separately by the WHO.

  • 2

    FA-LBCL typically arises in areas of chronic fibrin accumulation and is often discovered incidentally during surgery.

  • 3

    The case study details a 42-year-old female with FA-LBCL originating from cystic lymphangiomatous lesions in the adrenal gland.

  • 4

    Histological analysis revealed neoplastic cells with high proliferation rates and positive markers for CD20 and CD30.

  • 5

    FA-LBCL generally has a better prognosis than conventional DLBCL, especially when linked to chronic inflammation.

Original Source(s)

Case Report: Fibrin-associated large B-cell lymphoma developing within a cystic lesion of the adrenal gland: unexpected guest

  • by Haneen Al-Maghrabi, Bayan Ali Alghamdi

  • May 8, 2026

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