Effects of exercise on physical function and pain in adults with rheumatoid arthritis: an exit meta-analysis of randomized controlled trials - Takeaways - MDSpire

Effects of exercise on physical function and pain in adults with rheumatoid arthritis: an exit meta-analysis of randomized controlled trials

  • By

  • George A. Kelley

  • Kristi S. Kelley

  • Kim M. Huffman

  • July 8, 2026

  • 0 min

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  • 1

    Rheumatoid arthritis (RA) is a chronic autoimmune disease that leads to joint inflammation, reduced physical function, and increased pain.

  • 2

    The 2022 American College of Rheumatology Guidelines indicate moderate certainty that exercise improves physical function and reduces pain in adults with RA.

  • 3

    The study utilized the Doi–Abdulmajeed Trial Stability (DAts) index to assess the conclusiveness of meta-analyses regarding exercise effects on RA.

  • 4

    Data for the meta-analysis were derived from randomized controlled trials comparing exercise interventions to no exercise in RA patients.

  • 5

    The primary outcomes measured in the study were physical function and pain, using standardized mean difference as the effect size metric.

Original Source(s)

Effects of exercise on physical function and pain in adults with rheumatoid arthritis: an exit meta-analysis of randomized controlled trials

  • by George A. Kelley, Kristi S. Kelley, Kim M. Huffman

  • July 8, 2026

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