Case Report: Early documented infected pancreatic necrosis due to carbapenem-resistant Acinetobacter baumannii and concurrent Enterococcus faecium bacteremia: a salvage regimen with sulbactam-durlobactam and tigecycline - Takeaways - MDSpire

Case Report: Early documented infected pancreatic necrosis due to carbapenem-resistant Acinetobacter baumannii and concurrent Enterococcus faecium bacteremia: a salvage regimen with sulbactam-durlobactam and tigecycline

  • By

  • Man Li

  • Ying Fu

  • Ying Chen

  • Yunsong Yu

  • June 22, 2026

  • 0 min

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  • 1

    A 51-year-old male with severe acute pancreatitis developed infected pancreatic necrosis caused by carbapenem-resistant Acinetobacter baumannii.

  • 2

    The patient experienced persistent organ failure, abdominal compartment syndrome, and acute kidney injury requiring continuous renal replacement therapy.

  • 3

    Blood cultures confirmed Enterococcus faecium bacteremia, necessitating anti-enterococcal therapy alongside treatment for CRAB.

  • 4

    The combination of sulbactam-durlobactam and tigecycline was used effectively after carbapenem options were ruled out due to E. faecium resistance.

  • 5

    The patient showed clinical improvement and microbiological clearance after treatment, being discharged in stable condition on day 75.

Original Source(s)

Case Report: Early documented infected pancreatic necrosis due to carbapenem-resistant Acinetobacter baumannii and concurrent Enterococcus faecium bacteremia: a salvage regimen with sulbactam-durlobactam and tigecycline

  • by Man Li, Ying Fu, Ying Chen, Yunsong Yu

  • June 22, 2026

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