Prognostic accuracy of transcranial magnetic stimulation-induced motor evoked potentials on recovery of upper limb: a systematic review - Takeaways - MDSpire

Prognostic accuracy of transcranial magnetic stimulation-induced motor evoked potentials on recovery of upper limb: a systematic review

  • By

  • Johanna C. M. Schilder

  • Maurits H. J. Hoonhorst

  • Ralph de Vries

  • Gert Kwakkel

  • May 7, 2026

  • 0 min

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  • 1

    This systematic review evaluated the prognostic value of TMS-MEP for predicting upper limb recovery after stroke.

  • 2

    Sixteen prospective studies were included, all demonstrating low risk of bias, but only three met all technical standards for TMS testing.

  • 3

    TMS-MEP showed high sensitivity and specificity for predicting muscle strength, muscle synergies, and upper limb capacity post-stroke.

  • 4

    The predictive accuracy of TMS-MEP was consistent regardless of the timing of assessments after stroke onset.

  • 5

    Despite its predictive capabilities, TMS-MEP's accuracy in identifying individuals who will not regain upper limb function remains limited.

Original Source(s)

Prognostic accuracy of transcranial magnetic stimulation-induced motor evoked potentials on recovery of upper limb: a systematic review

  • by Johanna C. M. Schilder, Maurits H. J. Hoonhorst, Ralph de Vries, Gert Kwakkel

  • May 7, 2026

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