Afferent loop syndrome secondary to recurrent pancreatic adenocarcinoma post-Whipple procedure: case report - Takeaways - MDSpire

Afferent loop syndrome secondary to recurrent pancreatic adenocarcinoma post-Whipple procedure: case report

  • By

  • Justin Baik

  • Neil Hughes

  • Vladimir Ferrer

  • June 15, 2026

  • 0 min

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  • 1

    Afferent loop syndrome (ALS) is a rare complication after pancreaticoduodenectomy, primarily caused by recurrent malignancy.

  • 2

    A 62-year-old male with recurrent pancreatic adenocarcinoma developed ALS, presenting with abdominal pain, bowel obstruction, and sepsis.

  • 3

    Imaging confirmed obstruction of the pancreaticobiliary limb due to recurrent malignancy, leading to sepsis from Klebsiella pneumoniae.

  • 4

    Endoscopic decompression with a metal stent provided rapid clinical improvement and palliation for the patient.

  • 5

    Early recognition of ALS in post-Whipple patients is crucial to prevent severe complications and enable timely intervention.

Original Source(s)

Afferent loop syndrome secondary to recurrent pancreatic adenocarcinoma post-Whipple procedure: case report

  • by Justin Baik, Neil Hughes, Vladimir Ferrer

  • June 15, 2026

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