The Role of Gut Microbiota and Its Metabolites in Thyroid Disorders: Mechanisms and Functions

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The gut microbiota significantly influences thyroid health through the gut-thyroid axis, impacting disease pathogenesis.
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Microbial metabolites like short-chain fatty acids and bile acids play crucial roles in regulating thyroid hormone metabolism.
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Gut microbiota affects systemic immunity and intestinal barrier integrity, contributing to autoimmune thyroid diseases.
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Potential interventions include probiotics, prebiotics, and dietary changes to manage thyroid disorders effectively.
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The review integrates findings from human studies and animal models to enhance understanding of the gut-thyroid connection.

Frontiers In Immunology

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