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The Role of Gut Microbiota and Its Metabolites in Thyroid Disorders: Mechanisms and Functions

  • By

  • Yu, Xianqiang

  • April 27, 2026

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  • 1

    The gut microbiota significantly influences thyroid health through the gut-thyroid axis, impacting disease pathogenesis.

  • 2

    Microbial metabolites like short-chain fatty acids and bile acids play crucial roles in regulating thyroid hormone metabolism.

  • 3

    Gut microbiota affects systemic immunity and intestinal barrier integrity, contributing to autoimmune thyroid diseases.

  • 4

    Potential interventions include probiotics, prebiotics, and dietary changes to manage thyroid disorders effectively.

  • 5

    The review integrates findings from human studies and animal models to enhance understanding of the gut-thyroid connection.

Original Source(s)

Gut microbiota and its metabolites with thyroid diseases: Functions and mechanisms

  • by Yu, Xianqiang

  • April 27, 2026

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