Meta-analysis of efficacy of probiotics in reducing postoperative infections and improving outcomes in gastrointestinal surgery - Takeaways - MDSpire

Meta-analysis of efficacy of probiotics in reducing postoperative infections and improving outcomes in gastrointestinal surgery

  • By

  • Muhammad Shamim

  • May 8, 2026

  • 0 min

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  • 1

    Postoperative infections significantly contribute to morbidity and mortality after gastrointestinal surgery.

  • 2

    The meta-analysis included eight randomized controlled trials with a total of 755 participants evaluating probiotic efficacy.

  • 3

    Pooled analysis indicated a potential benefit of probiotics in reducing overall postoperative infections, though it narrowly missed statistical significance.

  • 4

    Multi-strain Lactobacillus and Bifidobacterium formulations showed a statistically significant reduction in postoperative infections.

  • 5

    The findings support the inclusion of specific probiotic regimens in Enhanced Recovery After Surgery protocols for gastrointestinal surgery patients.

Original Source(s)

Meta-analysis of efficacy of probiotics in reducing postoperative infections and improving outcomes in gastrointestinal surgery

  • by Muhammad Shamim

  • May 8, 2026

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