Acute injury characteristics predict chronic neuropathic pain development after spinal cord injury - Takeaways - MDSpire

Acute injury characteristics predict chronic neuropathic pain development after spinal cord injury

  • By

  • Kenneth A. Fond

  • Mayra Arellano

  • Abel Torres-Espin

  • Austin Chou

  • Xuan Bradfield

  • Sara L. Moncivais

  • J. Russell Huie

  • Debra D. Hemmerle

  • Anastasia V. Keller

  • Vineeta Singh

  • Lisa U. Pascual

  • Anthony M. DiGiorgio

  • Jason F. Talbott

  • William D. Whetstone

  • Jonathan Z. Pan

  • Philip R. Weinstein

  • Sanjay S. Dhall

  • Rajiv Saigal

  • Adam R. Ferguson

  • Jacqueline C. Bresnahan

  • Michael S. Beattie

  • Nikos Kyritsis

  • June 16, 2026

  • 0 min

Share

  • 1

    Neuropathic pain is a common complication after spinal cord injury (SCI), affecting patient quality of life significantly.

  • 2

    In a study of 61 SCI patients, 59% reported chronic neuropathic pain at 6 and 12 months post-injury.

  • 3

    Four acute care variables were identified as significant predictors of chronic neuropathic pain: systemic injuries, injury severity score, lower limb motor score, and sensory pinprick score.

  • 4

    The logistic regression model for predicting chronic neuropathic pain achieved a balanced accuracy of 74.3% and an AUC of 0.708.

  • 5

    The identified predictors are routinely measured in trauma centers, suggesting potential for clinical application in early intervention.

Original Source(s)

Acute injury characteristics predict chronic neuropathic pain development after spinal cord injury

  • by Kenneth A. Fond, Mayra Arellano, Abel Torres-Espin, Austin Chou, Xuan Bradfield, Sara L. Moncivais, J. Russell Huie, Debra D. Hemmerle, Anastasia V. Keller, Vineeta Singh, Lisa U. Pascual, Anthony M. DiGiorgio, Jason F. Talbott, William D. Whetstone, Jonathan Z. Pan, Philip R. Weinstein, Sanjay S. Dhall, Rajiv Saigal, Adam R. Ferguson, Jacqueline C. Bresnahan, Michael S. Beattie, Nikos Kyritsis

  • June 16, 2026

Related Content

2026 Brain and Spine Symposium Highlights Advances Across the Neurosciences

Over two days, specialists across neurology, neurosurgery and related subspecialties came together to discuss advances in stroke care, epilepsy, movement disorders, neurodegenerative disease, neuro-oncology, brain and spine surgery, interventional pain management and emerging technologies.

  • May 21, 2026

  • 1 min
Could Digital Twins Forecast Forensic Risk?

Researchers outline a proposed three-level framework spanning patient monitoring, ward operations, and forensic system planning.

Targeting endoplasmic reticulum stress: a novel therapeutic strategy for neuropathic pain