Investigation of the Relationship Between Ocular Surface Metrics and Corneal Higher-Order Aberrations in Patients with Dry Eye Disease: A Cross-Sectional Analysis - Takeaways - MDSpire

Investigation of the Relationship Between Ocular Surface Metrics and Corneal Higher-Order Aberrations in Patients with Dry Eye Disease: A Cross-Sectional Analysis

  • By

  • Yanmei Fang

  • Hezheng Zhou

  • Dan Xia

  • Kuiliang Yang

  • Han Zhang

  • Xiaoxi Deng

  • Yan Pan

  • Xiaohong Xiang

  • Tingting Fan

  • Xiaoli Jin

  • Wanju Yang

  • January 27, 2026

  • 0 min

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  • 1

    Dry eye disease (DED) is characterized by tear film instability, leading to symptoms like dryness, burning, and fluctuating vision.

  • 2

    Corneal higher-order aberrations (cHOAs) are linked to tear film instability in DED patients, affecting visual function.

  • 3

    The study involved 164 participants with varying degrees of DED severity, classified based on ocular surface metrics.

  • 4

    Ocular surface parameters, including OSDI, TBUT, CFS, and STT-I, were correlated with specific types of cHOAs.

  • 5

    The research aims to clarify the relationship between ocular surface metrics and cHOAs in patients with DED.

Original Source(s)

Investigation of the Relationship Between Ocular Surface Metrics and Corneal Higher-Order Aberrations in Patients with Dry Eye Disease: A Cross-Sectional Analysis

  • by Yanmei Fang, Hezheng Zhou, Dan Xia, Kuiliang Yang, Han Zhang, Xiaoxi Deng, Yan Pan, Xiaohong Xiang, Tingting Fan, Xiaoli Jin, Wanju Yang

  • January 27, 2026

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