Development of a Rapid Automated Point-of-Care Test for Hepatitis C Viral RNA on the DASH Rapid Polymerase Chain Reaction System - Takeaways - MDSpire

Development of a Rapid Automated Point-of-Care Test for Hepatitis C Viral RNA on the DASH Rapid Polymerase Chain Reaction System

  • By

  • Jennifer L Reed

  • Matthew A Butzler

  • Claudia A Hawkins

  • Yukari C Manabe

  • Jeffrey Holden

  • David L Thomas

  • Andrea L Cox

  • Sally M McFall

  • December 10, 2025

  • 0 min

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  • 1

    The DASH Rapid PCR System enables a 15-minute qualitative molecular test for Hepatitis C virus (HCV) at the point of care.

  • 2

    The DASH HCV assay demonstrates 100% positive and negative percent agreement compared to commercial platforms in a preliminary study.

  • 3

    This test can detect HCV genotypes 1–6 with a limit of detection of 200 IU/mL using a 100 μL specimen volume.

  • 4

    Molecular point-of-care testing for HCV is essential to improve access to diagnosis and treatment, especially in resource-limited settings.

  • 5

    The DASH HCV test supports same-day diagnosis and treatment, aligning with WHO guidelines for HCV elimination efforts.

Original Source(s)

Development of a Rapid Automated Point-of-Care Test for Hepatitis C Viral RNA on the DASH Rapid Polymerase Chain Reaction System

  • by Jennifer L Reed, Matthew A Butzler, Claudia A Hawkins, Yukari C Manabe, Jeffrey Holden, David L Thomas, Andrea L Cox, Sally M McFall

  • December 10, 2025

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