Stereotactic Intracranial Biopsy Outcomes: Insights from a 15-Year Institutional Review - Takeaways - MDSpire

Stereotactic Intracranial Biopsy Outcomes: Insights from a 15-Year Institutional Review

  • By

  • Vratko Himic

  • Sebastian Vargas-George

  • Maxon V. Knott

  • Vaidya Govindarajan

  • Seth S. Tigchelaar

  • Tyler M. Cardinal

  • Adham M. Khalafallah

  • Victor M. Lu

  • Hatun Mine Sahin

  • Arnold Lang

  • Zachary C. Gersey

  • Daniel M. Aaronson

  • Ricardo J. Komotar

  • Ashish H. Shah

  • Michael E. Ivan

  • April 21, 2026

  • 0 min

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  • 1

    Stereotactic biopsy is a minimally invasive procedure that provides rapid access to brain lesions, but obtaining adequate diagnostic tissue remains challenging.

  • 2

    Non-diagnostic biopsies are underreported in literature, complicating clinical decision-making and the development of universal management guidelines.

  • 3

    Re-biopsy after a non-diagnostic result is often successful, with conversion rates exceeding 75%, but outcomes without a definitive diagnosis are less studied.

  • 4

    This study analyzes non-diagnostic stereotactic biopsies over 15 years, focusing on clinical indications, lesion characteristics, and post-biopsy outcomes.

  • 5

    The research aims to improve transparency and inter-specialty dialogue regarding the management of non-diagnostic stereotactic brain biopsies.

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