The diagnostic yield of an elaborate workup for comorbidities in a real-life heart failure with preserved ejection fraction outpatient population - Takeaways - MDSpire

The diagnostic yield of an elaborate workup for comorbidities in a real-life heart failure with preserved ejection fraction outpatient population

  • By

  • Sanne G J Mourmans

  • Anouk Achten

  • Jerremy Weerts

  • Marijne Scheepers

  • Arantxa Barandiarán Aizpurua

  • Michiel Henkens

  • Nicole Uszko-Lencer

  • Hans-Peter Brunner-La Rocca

  • Christian Knackstedt

  • Vanessa P M van Empel

  • July 10, 2025

  • 0 min

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  • 1

    Comorbidities significantly impact heart failure with preserved ejection fraction (HFpEF), yet guidelines lack clear screening directives.

  • 2

    The study evaluated 501 HFpEF patients, revealing one additional comorbidity diagnosed per patient during standardized workup.

  • 3

    Commonly identified new comorbidities included sleep apnoea (33%) and iron deficiency (35%), alongside prevalent conditions like hypertension.

  • 4

    Existing comorbidities such as diabetes and obesity often received suboptimal treatment, highlighting gaps in guideline-directed therapy.

  • 5

    Routine screening for comorbidities in HFpEF patients enhances detection and management, improving overall patient care.

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