The informational dysregulation framework of addiction (IDFA): an information-processing model of relapse in opioid use disorder - Takeaways - MDSpire

The informational dysregulation framework of addiction (IDFA): an information-processing model of relapse in opioid use disorder

  • By

  • Ovie Martin Albert

  • July 13, 2026

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  • 1

    Opioid use disorder is characterized by high relapse risk and a disconnect between intention and behavior.

  • 2

    The Informational Dysregulation Framework of Addiction (IDFA) links neurobiology with lived experiences in relapse prevention.

  • 3

    IDFA conceptualizes relapse vulnerability as dysregulation in the brain's ability to predict and integrate information.

  • 4

    Relapse processes are organized into three domains: precision dysregulation, entropy disruption, and awareness impairment.

  • 5

    IDFA provides a framework for generating hypotheses regarding relapse prediction and intervention planning.

Original Source(s)

The informational dysregulation framework of addiction (IDFA): an information-processing model of relapse in opioid use disorder

  • by Ovie Martin Albert

  • July 13, 2026

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