Gestational Age as predictor of Postoperative Prognosis in Neonates with Pulmonary Atresia With Intact Ventricular Septum Undergoing Biventricular Repair

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Pulmonary atresia with intact ventricular septum (PA/IVS) is a rare critical congenital heart defect requiring biventricular repair.
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The study analyzed 97 pediatric patients with PA/IVS who underwent biventricular repair from 1999 to 2024.
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Each additional gestational week reduced the risk of adverse outcomes by 45% according to multivariable analysis.
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Term infants had a significantly lower risk of adverse outcomes compared to preterm infants, with an odds ratio of 0.14.
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A gestational age threshold effect was identified, with improved outcomes for infants born beyond 37.6 weeks.

Frontiers In Cardiovascular Medicine

by Chen, Shuo , Zhou, Ziqin , Hu, Luoming , tu, jiazichao , chen, weimin , tian, miao , Deng, Xiaohua , Li, Xiaohua , Su, Zhanhao , Chen, Jimei
June 22, 2026

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