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1
Acute invasive fungal rhinosinusitis (AIFRS) is primarily caused by Aspergillus and Trichoderma, often in immunocompromised patients.
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2
The case presented involves a 45-year-old male with AIFRS leading to secondary Central Retinal Artery Occlusion (CRAO), a rare complication.
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3
Diagnosis of AIFRS was confirmed through nasal endoscopy and histopathological examination, while CRAO was diagnosed using Fundus Fluorescein Angiography and Optical Coherence Tomography.
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4
AIFRS is highly lethal, with mortality rates ranging from 50% to 80%, and requires a multidisciplinary approach for effective diagnosis and treatment.
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5
The patient's condition deteriorated despite treatment, leading to death due to sepsis and septic shock, highlighting the aggressive nature of AIFRS.