Studies on allergic diseases and B cells in the past 20 years: a bibliometric analysis via CiteSpace and VOSviewer

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B lymphocytes are crucial modulators of IgE-mediated immunity and tolerance in allergic disorders, yet their roles remain incompletely understood.
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The bibliometric analysis identified a consistent increase in publications and citations related to B cells and allergic diseases over the past two decades.
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Key research areas include food allergy, asthma, and emerging interests in regulatory B cells and innate lymphoid cells.
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The study highlights the need for multicenter trials with standardized B-cell phenotyping to advance precision medicine in allergy.
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Recent findings suggest B cells have complex roles in allergic inflammation, functioning beyond IgE production to include immune modulation.

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