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1
The prevalence of Autism Spectrum Disorder (ASD) has increased significantly, raising questions about the coherence of DSM-5 diagnostic boundaries.
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2
The review identifies three failures in ASD diagnosis: classificatory, sociocultural, and methodological, impacting adult differential diagnosis.
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3
At least two neurobiologically distinct phenotypes of ASD are identified, with differing implications for assessment and diagnosis.
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4
The DSM-5 sensory criterion lacks diagnostic specificity, particularly affecting Type II presentations and the female phenotype.
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5
Minimum evidentiary standards for adult ASD diagnosis include structured history, multi-context observation, and systematic evaluation of alternative diagnoses.
