Hodgkin lymphoma with hypereosinophilia in a pediatric patient: case report and review of the literature - Takeaways - MDSpire

Hodgkin lymphoma with hypereosinophilia in a pediatric patient: case report and review of the literature

  • By

  • Rosa Margarita Cruz Osorio

  • Regina M. Navarro-Martin del Campo

  • Wangky Carolina Carrasco-Rivera

  • Lisette Paola Bruijnzeels-Ponce

  • Jesús Alejandro Gutiérrez-Ortiz

  • Hannali Quintero-Buenrostro

  • Violeta Salceda-Rivera

  • Manuel Donovan Martinez-Albarran

  • Diego Ugalde-Aviña

  • Veronica Soto Chavez

  • Fernando Sánchez-Zubieta

  • Oscar Gonzalez-Ramella

  • May 20, 2026

  • 0 min

Share

  • 1

    Hodgkin lymphoma (HL) accounts for 6% of pediatric cancers, with hypereosinophilia occurring in 15% of cases.

  • 2

    A 17-year-old female presented with weight loss, night sweats, and marked eosinophilia, leading to a diagnosis of nodular sclerosis classical Hodgkin lymphoma.

  • 3

    Blood tests revealed eosinophilia exceeding 97,000/µL, hypoalbuminemia, and elevated lactate dehydrogenase levels.

  • 4

    The patient underwent OEPA/COPDAC treatment followed by radiotherapy, achieving a complete metabolic response.

  • 5

    This case highlights the rare association between classical Hodgkin lymphoma and extreme hypereosinophilia, emphasizing the need for awareness in diagnosis.

Original Source(s)

Related Content