Gut Instinct - Takeaways - MDSpire

Gut Instinct

  • By

  • The Ophthalmologist

  • January 6, 2026

  • 3 min

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  • 1

    Gastrectomy is associated with a higher long-term risk of developing dry eye disease (DED) according to a Korean cohort study.

  • 2

    The study analyzed over 5,400 gastrectomy patients and nearly 22,000 matched controls to assess ocular surface health.

  • 3

    Total gastrectomy significantly increased DED risk with an adjusted hazard ratio of 1.40, especially in older males and lower-income groups.

  • 4

    Colectomy did not show an increased risk of DED, indicating the specific impact of upper GI tract alterations on ocular health.

  • 5

    The findings suggest that post-gastrectomy patients require closer monitoring for dry eye symptoms and nutritional assessments.

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