A prediction for sepsis in adult patients with severe cerebrovascular disease from neurological intensive care unit - Takeaways - MDSpire

A prediction for sepsis in adult patients with severe cerebrovascular disease from neurological intensive care unit

  • By

  • Haiyang Sun

  • Shuyun Sun

  • Yan Huang

  • Jingbo Sun

  • Chuanchuan Yu

  • Lixin Wang

  • Xiao Cheng

  • July 7, 2026

  • 0 min

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  • 1

    Sepsis prevalence in acute moderate-to-severe stroke patients was found to be 12.1% in the neurological intensive care unit.

  • 2

    The study identified four significant variables for predicting sepsis: Hyperlipidaemia, IL-10, NIHSS, and Blood creatinine.

  • 3

    A prediction model for sepsis was developed using multi-factorial logistic regression, achieving an AUC of 0.816.

  • 4

    Patients with comorbidity sepsis had lower GCS scores and higher NIHSS scores compared to those without sepsis.

  • 5

    Blood biomarkers IL-10, MIP-1β, TNF-α, nNOS, iNOS, MMP-9, S-100β, and ET-1 were assessed within 48 hours after symptom onset.

Original Source(s)

A prediction for sepsis in adult patients with severe cerebrovascular disease from neurological intensive care unit

  • by Haiyang Sun, Shuyun Sun, Yan Huang, Jingbo Sun, Chuanchuan Yu, Lixin Wang, Xiao Cheng

  • July 7, 2026

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