Incidence of Recurrent Invasive Pneumococcal Disease in Canada

By
Leah J. Ricketson
Altynay Shigayeva
Irina Rajakumar
Zoe Zhong
Kazi Hassan
Irene Martin
Alyssa Golden
Allison J. McGeer
James D. Kellner
Calgary Area Epidemiology Research Group and the Toronto Invasive Bacterial Diseases Network
Chingiz Amirov
Neil Rau
Danny Chen
Jeff Powis
Amna Faheem
Kevin Katz
Valerie Sales
Samir Patel
Abdelbaset Belhaj
Reena Lovinsky
David Rose
Christie Vermeiren
Tony Mazzulli
Jennie Johnstone
Karen Green
Michael Lingley
Andrew Simor
Samira Mubareka
Sigmund Krajden
Larissa Matukas
Sharon Walmsley
Medina Saffie
Daniel Ricciuto
Krystyna Ostrowska
David Richardson
Shannon N Pyra
Joslyn D Gray
July 7, 2026
0 min

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Invasive pneumococcal disease (IPD) remains a significant health issue despite vaccination efforts in Canada.
2

Recurrent IPD (rIPD) occurs in 2.2% to 5.3% of IPD cases, with an incidence 27 times that of primary IPD.
3

Immunocompromising conditions are recognized risk factors for rIPD, potentially indicating underlying immune disorders.
4

The study analyzed data from 8676 IPD episodes in 8353 patients between 2004 and 2022 across Calgary and Toronto.
5

Current vaccination guidelines do not consider prior IPD as a criterion for pneumococcal vaccination.

Jama Network Open

by Leah J. Ricketson, Altynay Shigayeva, Irina Rajakumar, Zoe Zhong, Kazi Hassan, Irene Martin, Alyssa Golden, Allison J. McGeer, James D. Kellner, Calgary Area Epidemiology Research Group and the Toronto Invasive Bacterial Diseases Network, Chingiz Amirov, Neil Rau, Danny Chen, Jeff Powis, Amna Faheem, Kevin Katz, Valerie Sales, Samir Patel, Abdelbaset Belhaj, Reena Lovinsky, David Rose, Christie Vermeiren, Tony Mazzulli, Jennie Johnstone, Karen Green, Michael Lingley, Andrew Simor, Samira Mubareka, Sigmund Krajden, Larissa Matukas, Sharon Walmsley, Medina Saffie, Daniel Ricciuto, Krystyna Ostrowska, David Richardson, Shannon N Pyra, Joslyn D Gray
July 7, 2026

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