Risk management plan adherence and clinical outcomes in patients receiving targeted therapies - Takeaways - MDSpire

Risk management plan adherence and clinical outcomes in patients receiving targeted therapies

  • By

  • Li-Fong Wang

  • Hsiu-Lan Li

  • Yi-Hsien Huang

  • Chun-Hao Yin

  • June 16, 2026

  • 0 min

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  • 1

    Targeted therapies for autoimmune diseases include bDMARDs, tsDMARDs, and CAR-T therapy, improving disease control and long-term outcomes.

  • 2

    Risk management programs (RMPs) are essential for addressing safety concerns associated with targeted therapies, including infection screening and prophylaxis.

  • 3

    Real-world adherence to RMPs may vary, particularly after treatment initiation and during transitions to biosimilars.

  • 4

    The study evaluated RMP adherence and its association with infection-related outcomes in patients receiving targeted therapies.

  • 5

    Primary outcomes of interest included Pneumocystis jirovecii pneumonia, major adverse cardiovascular events, and all-cause mortality.

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