Vitamin D may ease cancer treatment skin toxicity

Most patients reported symptom relief within 10 days, while 73% continued anticancer therapy without interruption.

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High-dose oral vitamin D improved skin toxicity symptoms in cancer patients undergoing chemotherapy and radiation without adverse events.
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A retrospective study involved 33 patients, with 87% reporting symptom relief and 77% showing clinician-assessed improvement within 10 days.
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Erythema scores decreased significantly from 4.36 at baseline to 2.21 by day 10, indicating a notable reduction in skin toxicity.
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Seventy-three percent of patients continued anticancer therapy without interruption, while 12% discontinued due to severe skin toxic effects.
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The study's limitations included its retrospective design, lack of a control group, and potential biases, prompting calls for further research.

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