F2-Isoprostanes Are Associated With Increased Fracture Risk in Type 2 Diabetes - Takeaways - MDSpire
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Elevated Plasma F2-Isoprostanes Correlate with Higher Fracture Risk in Individuals with Type 2 Diabetes

  • By

  • Bowen Wang

  • Ruban Dhaliwal

  • Susan K Ewing

  • Ann V Schwartz

  • Deepak Vashishth

  • November 8, 2024

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  • 1

    Elevated plasma F2-isoprostanes are significantly associated with increased fracture risk in older adults with type 2 diabetes.

  • 2

    A 93% increase in fracture risk correlates with each standard deviation increase in log plasma F2-isoprostanes in the T2D group.

  • 3

    No significant association between plasma F2-isoprostanes and fracture risk was found in the nondiabetes group.

  • 4

    Log plasma F2-isoprostanes moderately correlate with declines in total hip BMD in individuals with type 2 diabetes.

  • 5

    The study highlights the need for clinical markers beyond BMD to assess fracture risk in individuals with type 2 diabetes.

Original Source(s)

F2-Isoprostanes Are Associated With Increased Fracture Risk in Type 2 Diabetes

  • by Bowen Wang, Ruban Dhaliwal, Susan K Ewing, Ann V Schwartz, Deepak Vashishth

  • November 8, 2024

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