GLP-1 Analysis: Riding the Wave of Peptide Innovation

The remarkable commercial success of GLP-1 receptor agonists is fueling investment, accelerating science, and creating new analytical challenges. Here, we outline the hurdles these peptides present, explore methods for impurity profiling and structural characterization, and consider strategies to keep pace with this fast-moving field.

By
Amanda M. Guiraldelli
Piotr Alvarez
Koen Sandra
April 9, 2026
18 min

The Medicine Maker

Top Institutions in Endocrinology

Brief introduction explaining scope and methodology.

#1

Joslin Diabetes Center

Boston, MA
Key Differentiators
- Diabetes Research
- Endocrinology
- Metabolic Disease
#2

Mayo Clinic

Rochester, MN
Key Differentiators
- Endocrinology
- Obesity Medicine
- Clinical Pharmacology
#3

University of California, San Francisco (UCSF)

San Francisco, CA
Key Differentiators
- Endocrinology
- Metabolic Research
- Pharmacology
#4

Harvard Medical School

Boston, MA
Key Differentiators
- Endocrinology
- Metabolic Disease
- Translational Medicine
#5

Massachusetts Institute of Technology (MIT)

Cambridge, MA
Key Differentiators
- Biomedical Engineering
- Drug Delivery
- Peptide Therapeutics