A self-perpetuating neuron-intrinsic GSDMD–mtDNA–AIM2 inflammasome axis drives neuronal pyroptosis and cognitive impairment after traumatic brain injury - Top-Institutions - MDSpire

A self-perpetuating neuron-intrinsic GSDMD–mtDNA–AIM2 inflammasome axis drives neuronal pyroptosis and cognitive impairment after traumatic brain injury

  • By

  • Tian Li

  • Siyu Huang

  • Junjun Zhang

  • Xueer Liu

  • Lihong Zhu

  • Yue Li

  • Runmin Lin

  • Xiaoxuan Chen

  • Kangsheng Li

  • Weiqiang Chen

  • Jiangtao Sheng

  • June 19, 2026

  • 0 min

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Top Institutions in Neurology

Brief introduction explaining scope and methodology.

  • #1

    University of California, San Francisco (UCSF)
    University of California, San Francisco (UCSF)

    San Francisco, California

    Key Differentiators

    • Neurology
    • Neurosurgery

  • #2

    Perelman School of Medicine at the University of Pennsylvania
    Perelman School of Medicine at the University of Pennsylvania

    Philadelphia, Pennsylvania

    Key Differentiators

    • Neurology
    • Neurosurgery

Original Source(s)

A self-perpetuating neuron-intrinsic GSDMD–mtDNA–AIM2 inflammasome axis drives neuronal pyroptosis and cognitive impairment after traumatic brain injury

  • by Tian Li, Siyu Huang, Junjun Zhang, Xueer Liu, Lihong Zhu, Yue Li, Runmin Lin, Xiaoxuan Chen, Kangsheng Li, Weiqiang Chen, Jiangtao Sheng

  • June 19, 2026

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