Explainable machine learning for osteoporosis detection in patients with osteopenia: model development and validation using routine clinical data from an Asian cohort - Top-Institutions - MDSpire

Development and Validation of an Explainable Machine Learning Model for Osteoporosis Identification in Osteopenic Patients Using Routine Clinical Data from an Asian Population

  • By

  • Xiuzhen Zhang

  • Li Zhao

  • Han Wu

  • Fengyi Yuan

  • Weiqing Wu

  • Yan Wu

  • Wei Wang

  • July 20, 2026

Share

Top Institutions in Endocrinology

Brief introduction explaining scope and methodology.

  • #1

    Shenzhen People’s Hospital
    Shenzhen People’s Hospital

    Shenzhen, Guangdong

    Key Differentiators

    • Endocrinology

  • #2

    First Affiliated Hospital of Fujian Medical University
    First Affiliated Hospital of Fujian Medical University

    Fuzhou, Fujian

    Key Differentiators

    • Endocrinology

  • #3

    Yuebei People's Hospital
    Yuebei People's Hospital

    Yuebei, Guangdong

    Key Differentiators

    • Endocrinology

Original Source(s)

Explainable machine learning for osteoporosis detection in patients with osteopenia: model development and validation using routine clinical data from an Asian cohort

  • by Xiuzhen Zhang, Li Zhao, Han Wu, Fengyi Yuan, Weiqing Wu, Yan Wu, Wei Wang

  • July 20, 2026

Related Content

Higher Steroid Exposure Linked to Systemic Adverse Events in CRSwNP

Higher annual oral corticosteroid exposure was associated with greater odds of systemic adverse events, with avascular bone necrosis and pneumonia showing dose-dependent associations with cumulative dose and osteoporosis associated with longer annual exposure duration.

Simplified Bone Age Method May Aid Review

Single-bone approach showed close agreement with Greulich-Pyle assessments in adolescents, particularly among experienced raters

OI Therapy Raised BMD, Not Fracture Benefit

Teriparatide followed by zoledronic acid increased bone mineral density but did not reduce fracture risk compared with standard care in adults with osteogenesis imperfecta.