Molecular mechanisms of KMT2C alterations in gastrointestinal cancers: enhancer network destabilization, lineage plasticity, and clinical translation - Top-Institutions - MDSpire

Investigating the Role of KMT2C Alterations in Gastrointestinal Cancers: Disruption of Enhancer Networks, Lineage Flexibility, and Implications for Clinical Practice

  • By

  • Xintao Zeng

  • Pei Yang

  • Tao Wang

  • Ruizi Shi

  • Chuan Qin

  • Lun Zhang

  • Ting Jiang

  • Xi Chen

  • Hua Luo

  • Jihong Wei

  • Haiyan Hu

  • Decai Wang

  • Jianjun Wang

  • May 28, 2026

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Top Institutions in Oncology

Brief introduction explaining scope and methodology.

  • #1

    Dana-Farber/Harvard Cancer Center
    Dana-Farber/Harvard Cancer Center

    Boston, Massachusetts

    Key Differentiators

    • Oncology
    • Gastrointestinal Cancer

  • #2

    Memorial Sloan Kettering Cancer Center
    Memorial Sloan Kettering Cancer Center

    New York, New York

    Key Differentiators

    • Oncology
    • Gastrointestinal Cancer

Original Source(s)

Molecular mechanisms of KMT2C alterations in gastrointestinal cancers: enhancer network destabilization, lineage plasticity, and clinical translation

  • by Xintao Zeng, Pei Yang, Tao Wang, Ruizi Shi, Chuan Qin, Lun Zhang, Ting Jiang, Xi Chen, Hua Luo, Jihong Wei, Haiyan Hu, Decai Wang, Jianjun Wang

  • May 28, 2026

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