Intrathecal nivolumab in metastatic solid tumors with leptomeningeal disease: dose escalation part of the multicenter IT-PD1/NOA-26 phase 1 trial

• By

• Ghazaleh Tabatabai

• Isabel Ramirez

• Beatrix Welte

• Paula Bombach

• Hannes Becker

• Denise Bernhardt

• Regine Mayer-Steinacker

• Friedegund Meier

• Nicolas Neidert

• Roland Roelz

• Iris Mildenberger

• Lukas Bunse

• Michael Platten

• Ulrich Herrlinger

• Uwe M. Martens

• Ulrike Ernemann

• Manuela Neumann

• Marcos Tatagiba

• Lina Maria Serna-Higuita

• Peter Martus

• Mirjam Renovanz

• June 4, 2026

• 0 min

• Nature Cancer