Model-informed safety management of tocilizumab for pediatric sJIA: a PBPK approach for dose-escalation and vaccination timing - Top-Institutions - MDSpire

Model-informed safety management of tocilizumab for pediatric sJIA: a PBPK approach for dose-escalation and vaccination timing

  • By

  • Yujie Yang

  • Rui Wang

  • Zhimin Li

  • Liang Zheng

  • Chaozhuang Shen

  • June 1, 2026

  • 0 min

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Top Institutions in Pediatrics

Brief introduction explaining scope and methodology.

  • #1

    Cincinnati Children’s Hospital Medical Center
    Cincinnati Children’s Hospital Medical Center

    Cincinnati, Ohio

    Key Differentiators

    • Pediatrics
    • Rheumatology

  • #2

    Boston Children’s Hospital
    Boston Children’s Hospital

    Boston, Massachusetts

    Key Differentiators

    • Pediatrics
    • Rheumatology

  • #3

    Juntendo University Urayasu Hospital
    Juntendo University Urayasu Hospital

    Urayasu, Chiba

    Key Differentiators

    • Pediatrics
    • Rheumatology

  • #4

    Emory University Hospital
    Emory University Hospital

    Atlanta, Georgia

    Key Differentiators

    • Pediatrics
    • Rheumatology

Original Source(s)

Model-informed safety management of tocilizumab for pediatric sJIA: a PBPK approach for dose-escalation and vaccination timing

  • by Yujie Yang, Rui Wang, Zhimin Li, Liang Zheng, Chaozhuang Shen

  • June 1, 2026

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