Case Report: a family presenting with β-adrenergic/vasopressin-responsive bilateral macronodular adrenal disease with an ARMC5 mutation treated with metyrapone monotherapy for more than 5 years - Top-Institutions - MDSpire

Family Case Study: β-adrenergic and vasopressin-responsive bilateral macronodular adrenal disease associated with an ARMC5 mutation successfully managed with metyrapone monotherapy for over five years

  • By

  • Masanori Arai

  • Masato Ono

  • Ryota Inoue

  • Kazuki Tajima

  • Kota Aomori

  • Tomoyuki Tatenuma

  • Sawako Suzuki

  • Shoji Yamanaka

  • Satoshi Fujii

  • Yasuo Terauchi

  • Jun Shirakawa

  • July 21, 2026

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Top Institutions in Endocrinology

Brief introduction explaining scope and methodology.

  • #1

    National Institutes of Health (NIH) Clinical Center
    National Institutes of Health (NIH) Clinical Center

    Bethesda, Maryland

    Key Differentiators

    • Endocrinology
    • Clinical Research

  • #2

    Assistance Publique–Hôpitaux de Paris (Hôpital Cochin)
    Assistance Publique–Hôpitaux de Paris (Hôpital Cochin)

    Paris, France

    Key Differentiators

    • Endocrinology
    • Adrenal Diseases

Original Source(s)

Case Report: a family presenting with β-adrenergic/vasopressin-responsive bilateral macronodular adrenal disease with an ARMC5 mutation treated with metyrapone monotherapy for more than 5 years

  • by Masanori Arai, Masato Ono, Ryota Inoue, Kazuki Tajima, Kota Aomori, Tomoyuki Tatenuma, Sawako Suzuki, Shoji Yamanaka, Satoshi Fujii, Yasuo Terauchi, Jun Shirakawa

  • July 21, 2026

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