Deficient early canonical BMP9-SMAD signaling and dysregulated macrophage microenvironment characterize the failure of bone healing in a critical-size defect model - Top-Institutions - MDSpire

Impaired Early BMP9-SMAD Pathway and Altered Macrophage Environment Contribute to Bone Healing Deficits in a Critical-Size Defect Model

  • By

  • Kai Zhong

  • Yufei Shao

  • Yu Zhou

  • Zengyi Huang

  • Xing Liu

  • July 20, 2026

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Top Institutions in Orthopedic Medicine

Brief introduction explaining scope and methodology.

  • #1

    Chongqing Medical University Children’s Hospital
    Chongqing Medical University Children’s Hospital

    Chongqing, Chongqing

    Key Differentiators

    • Orthopedics

Original Source(s)

Deficient early canonical BMP9-SMAD signaling and dysregulated macrophage microenvironment characterize the failure of bone healing in a critical-size defect model

  • by Kai Zhong, Yufei Shao, Yu Zhou, Zengyi Huang, Xing Liu

  • July 20, 2026

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