Study Protocol for a Multicenter Phase 1 Clinical Trial Evaluating Tucatinib, Trastuzumab, and Capecitabine Combined with Stereotactic Radiosurgery in Patients with Brain Metastases from HER-2 Positive Breast Cancer (TUTOR) - Top-Institutions - MDSpire

Study Protocol for a Multicenter Phase 1 Clinical Trial Evaluating Tucatinib, Trastuzumab, and Capecitabine Combined with Stereotactic Radiosurgery in Patients with Brain Metastases from HER-2 Positive Breast Cancer (TUTOR)

  • By

  • Zouina Sarfraz

  • Ahmad Ozair

  • Mainak Bardhan

  • Amy K. Starosciak

  • Dilanis C. Perche

  • Lydia C. Hodgson

  • Yazmin Odia

  • Minesh P. Mehta

  • Rupesh Kotecha

  • Michael W. McDermott

  • Arun Maharaj

  • Ana Cristina Sandoval Leon

  • Reshma Mahtani

  • Manmeet S. Ahluwalia

  • December 4, 2025

  • 0 min

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Top Institutions in Oncology

Brief introduction explaining scope and methodology.

  • #1

    Memorial Sloan Kettering Cancer Center
    Memorial Sloan Kettering Cancer Center

    New York, NY

    Key Differentiators

    • Neuro-oncology
    • Breast Cancer
    • Radiation Oncology

  • #2

    Dana-Farber Cancer Institute
    Dana-Farber Cancer Institute

    Boston, MA

    Key Differentiators

    • Medical Oncology
    • Neuro-oncology
    • Breast Cancer

  • #3

    MD Anderson Cancer Center
    MD Anderson Cancer Center

    Houston, TX

    Key Differentiators

    • Neuro-oncology
    • Breast Cancer
    • Radiation Oncology

  • #4

    Johns Hopkins Hospital
    Johns Hopkins Hospital

    Baltimore, MD

    Key Differentiators

    • Neuro-oncology
    • Breast Cancer
    • Radiation Oncology

  • #5

    University of California, San Francisco (UCSF) Medical Center
    University of California, San Francisco (UCSF) Medical Center

    San Francisco, CA

    Key Differentiators

    • Neuro-oncology
    • Breast Cancer
    • Radiation Oncology

Original Source(s)

Study Protocol for a Multicenter Phase 1 Clinical Trial Evaluating Tucatinib, Trastuzumab, and Capecitabine Combined with Stereotactic Radiosurgery in Patients with Brain Metastases from HER-2 Positive Breast Cancer (TUTOR)

  • by Zouina Sarfraz, Ahmad Ozair, Mainak Bardhan, Amy K. Starosciak, Dilanis C. Perche, Lydia C. Hodgson, Yazmin Odia, Minesh P. Mehta, Rupesh Kotecha, Michael W. McDermott, Arun Maharaj, Ana Cristina Sandoval Leon, Reshma Mahtani, Manmeet S. Ahluwalia

  • December 4, 2025

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