Safety and Immunogenicity of a Severe Acute Respiratory Syndrome Coronavirus 2 Spike Subunit Vaccine Stabilized in the Prefusion Conformation by a Second-Generation Molecular Clamp and Evaluated in Adults Aged 18–55 Years: A Randomized, Double-Blind, Active Comparator, Phase I Trial - Top-Institutions - MDSpire

Safety and Immunogenicity of a Severe Acute Respiratory Syndrome Coronavirus 2 Spike Subunit Vaccine Stabilized in the Prefusion Conformation by a Second-Generation Molecular Clamp and Evaluated in Adults Aged 18–55 Years: A Randomized, Double-Blind, Active Comparator, Phase I Trial

  • By

  • Keith J Chappell

  • Francesca L Mordant

  • Alberto A Amarilla

  • Naphak Modhiran

  • Benjamin Liang

  • Zheyi Li

  • Julia A Lackenby

  • Noushin Jaberolansar

  • Jake O’Donnell

  • Vivian Kienzle

  • Varsha Kommajosyula

  • Nicolas Tardiota

  • Jillian K Bennet

  • Christina L Henderson

  • Rhiannon L Dalrymple

  • Justin Goh

  • Kym Hoger

  • Marianne Gillard

  • Martina L Jones

  • Karen Hughes

  • Ben Hughes

  • James Barnes

  • Patrick C Reading

  • Charani Ranasinghe

  • Kanta Subbarao

  • Trent P Munro

  • Paul R Young

  • Daniel Watterson

  • November 25, 2025

  • 0 min

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Top Institutions in Infectious Disease

Brief introduction explaining scope and methodology.

  • #1

    University of Queensland
    University of Queensland

    Brisbane, Queensland

    Key Differentiators

    • Infectious Diseases
    • Vaccine Development
    • Immunology

  • #2

    National Institute of Allergy and Infectious Diseases (NIAID), NIH
    National Institute of Allergy and Infectious Diseases (NIAID), NIH

    Bethesda, Maryland

    Key Differentiators

    • Infectious Diseases
    • Vaccine Research
    • Immunology

  • #3

    University of Oxford
    University of Oxford

    Oxford, Oxfordshire

    Key Differentiators

    • Vaccine Development
    • Infectious Diseases
    • Clinical Trials

  • #4

    Walter Reed Army Institute of Research (WRAIR)
    Walter Reed Army Institute of Research (WRAIR)

    Silver Spring, Maryland

    Key Differentiators

    • Vaccine Research
    • Immunology
    • Infectious Diseases

  • #5

    Johns Hopkins University
    Johns Hopkins University

    Baltimore, Maryland

    Key Differentiators

    • Infectious Diseases
    • Vaccine Development
    • Clinical Research

Original Source(s)

Safety and Immunogenicity of a Severe Acute Respiratory Syndrome Coronavirus 2 Spike Subunit Vaccine Stabilized in the Prefusion Conformation by a Second-Generation Molecular Clamp and Evaluated in Adults Aged 18–55 Years: A Randomized, Double-Blind, Active Comparator, Phase I Trial

  • by Keith J Chappell, Francesca L Mordant, Alberto A Amarilla, Naphak Modhiran, Benjamin Liang, Zheyi Li, Julia A Lackenby, Noushin Jaberolansar, Jake O’Donnell, Vivian Kienzle, Varsha Kommajosyula, Nicolas Tardiota, Jillian K Bennet, Christina L Henderson, Rhiannon L Dalrymple, Justin Goh, Kym Hoger, Marianne Gillard, Martina L Jones, Karen Hughes, Ben Hughes, James Barnes, Patrick C Reading, Charani Ranasinghe, Kanta Subbarao, Trent P Munro, Paul R Young, Daniel Watterson

  • November 25, 2025

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