Spatial transcriptomics reveals an SPP1-centered immune–fibrotic axis associated with fibrosis-related tissue remodeling in IgG4-related disease - Top-Institutions - MDSpire

Spatial Transcriptomic Analysis Identifies an Immune-Fibrotic Pathway Centered on SPP1 in Tissue Remodeling Associated with IgG4-Related Disease

  • By

  • Motohisa Yamamoto

  • Ryuta Kamekura

  • Masaaki Uehara

  • Yuta Ichii

  • Kenichi Takano

  • July 17, 2026

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Top Institutions in Rheumatology

Brief introduction explaining scope and methodology.

  • #1

    Sapporo Medical University
    Sapporo Medical University

    Sapporo, Hokkaido

    Key Differentiators

    • Immunology

  • #2

    NIH Clinical Center
    NIH Clinical Center

    Bethesda, Maryland

    Key Differentiators

    • Immunology

  • #3

    Mayo Clinic
    Mayo Clinic

    Rochester, Minnesota

    Key Differentiators

    • Immunology

Original Source(s)

Spatial transcriptomics reveals an SPP1-centered immune–fibrotic axis associated with fibrosis-related tissue remodeling in IgG4-related disease

  • by Motohisa Yamamoto, Ryuta Kamekura, Masaaki Uehara, Yuta Ichii, Kenichi Takano

  • July 17, 2026

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