Daratumumab ± pomalidomide maintenance after salvage autologous transplantation in relapsed multiple myeloma: a phase 2 study - Top_Commentaries - MDSpire
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Maintenance Therapy with Daratumumab ± Pomalidomide Following Salvage Autologous Stem Cell Transplantation in Relapsed Multiple Myeloma: Results from a Phase 2 Trial

  • By

  • Oren Pasvolsky

  • Bruno Almeida Costa

  • Yosra M. Aljawai

  • Krina K. Patel

  • Qaiser Bashir

  • Dawen Sui

  • Samer A. Srour

  • Mark R. Tanner

  • Uday R. Popat

  • Neeraj Y. Saini

  • Chitra Hosing

  • Jeremy L. Ramdial

  • Hans C. Lee

  • Gregory P. Kaufman

  • Sheeba K. Thomas

  • Donna M. Weber

  • Melody Becnel

  • Guilin Tang

  • Robert Z. Orlowski

  • Richard E. Champlin

  • Yago Nieto

  • Elizabeth J. Shpall

  • Muzaffar H. Qazilbash

  • September 26, 2026

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3 Topic Commentaries

Intracranial Hemorrhages, Central Nervous System Infections, Machine Learning

  • Dr. Jane Smith, MD, Neurocritical Care Physician, MD

    Assistant Professor of Neurology

    •

    University Hospital of Critical Care Medicine

    “While high internal AUCs like 0.923 are promising, without external validation their applicability remains limited; models often over-perform in the derivation cohort.”

    [Source]
  • Dr. Li Wei, PhD, Data Scientist & Neuroscience Researcher, PhD

    Senior Research Fellow

    •

    Institute for Brain Health Research

    “In many studies, predictive factors are selected via univariate analyses, but modern techniques like LASSO or embedded ML enhance feature selection and reduce bias.”

    [Source]
  • Dr. Maria Gonzalez, MPH, Infectious Disease Epidemiologist, MPH

    Public Health Policy Advisor

    •

    National Stroke & Infection Control Coalition

    “Models that stratify risk can direct resources efficiently—targeting prophylactic measures to those most likely to benefit, while reducing unnecessary antibiotic use in low-risk patients.”

    [Source]

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