Erythropoietin Treatment in Neonatal Hypoxic-Ischemic Encephalopathy: Results from a Randomized Clinical Study
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By
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Helen G. Liley
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Rod W. Hunt
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Rachel L. O’Connell
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Malcolm R. Battin
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Iona Novak
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Yvonne W. Wu
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Roberta Ballard
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Lisa Askie
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Nadia Badawi
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Alpana Ghadge
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Susan E. Jacobs
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Sandra E. Juul
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Lucille Sebastian
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Deepika Wagh
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R. John Simes
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PAEAN Study Investigators
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Shannon Clough
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Jennifer Bowen
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Paul Colditz
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Girsih Deshpande
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Lisa Gold
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Wendy Hague
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Kei Lui
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Dominic Wilkinson
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Nicola Austin
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Sarah Bellhouse
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Max Berry
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Clare Collins
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Amanda Dyson
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Antonio G de Paoli
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Koert de Waal
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Bevan Headley
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Leah Hickey
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James Holberton
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David Hou
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Alison L Kent
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Vinayak Kodur
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Richard Mausling
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Scott Morris
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Arun Nair
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David Osborn
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Victor Samuel Rajadurai
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Nadia Schmidt
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Jason Tan
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Mark B Tracy
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Flora Y Wong
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Sarah Finlayson
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Shannon Hunt
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Carbo Yeung
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Laurence Ralston
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October 1, 2026
3 Topic Commentaries
Intracranial Hemorrhages, Central Nervous System Infections, Machine Learning
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Dr. Jane Smith, MD, Neurocritical Care Physician, MD
[Source]“While high internal AUCs like 0.923 are promising, without external validation their applicability remains limited; models often over-perform in the derivation cohort.”
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Dr. Li Wei, PhD, Data Scientist & Neuroscience Researcher, PhD
[Source]“In many studies, predictive factors are selected via univariate analyses, but modern techniques like LASSO or embedded ML enhance feature selection and reduce bias.”
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Dr. Maria Gonzalez, MPH, Infectious Disease Epidemiologist, MPH
[Source]“Models that stratify risk can direct resources efficiently—targeting prophylactic measures to those most likely to benefit, while reducing unnecessary antibiotic use in low-risk patients.”
