Utilizing High-Efficiency Particulate Air Filters to Mitigate Winter Respiratory Infections in Long-Term Care Facilities: The AFRI-c Study
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By
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Alastair D. Hay
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Rachel C. M. Brierley
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Nick Turner
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Joanna C. Thorn
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Sophie Rees
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Claire E. Brown
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Laurel Campbell-Smith
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Eleanor A. Gidman
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Emily J. Henderson
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Graziella Mazza
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Gemma Morgan
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Derren Ready
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Craig Riddington
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Jane Sprackman
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Jodi Taylor
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Tomas Welsh
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Ruth Kipping
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September 1, 2026
3 Topic Commentaries
Intracranial Hemorrhages, Central Nervous System Infections, Machine Learning
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Dr. Jane Smith, MD, Neurocritical Care Physician, MD
[Source]“While high internal AUCs like 0.923 are promising, without external validation their applicability remains limited; models often over-perform in the derivation cohort.”
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Dr. Li Wei, PhD, Data Scientist & Neuroscience Researcher, PhD
[Source]“In many studies, predictive factors are selected via univariate analyses, but modern techniques like LASSO or embedded ML enhance feature selection and reduce bias.”
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Dr. Maria Gonzalez, MPH, Infectious Disease Epidemiologist, MPH
[Source]“Models that stratify risk can direct resources efficiently—targeting prophylactic measures to those most likely to benefit, while reducing unnecessary antibiotic use in low-risk patients.”
