Correction Notice: Inhibition of TRIP-Br2, a key modulator of lipid breakdown, thermogenic activity, and oxidative processes, mitigates obesity and insulin resistance linked to diet.
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By
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Chong Wee Liew
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Jeremie Boucher
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Jit Kong Cheong
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Cecile Vernochet
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Ho-Jin Koh
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Cristina Mallol
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Kristy Townsend
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Dominique Langin
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Dan Kawamori
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Jiang Hu
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Yu-Hua Tseng
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Marc K Hellerstein
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Stephen R Farmer
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Laurie Goodyear
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Alessandro Doria
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Matthias Blüher
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Stephen I-Hong Hsu
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Rohit N Kulkarni
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September 9, 2026
3 Topic Commentaries
Intracranial Hemorrhages, Central Nervous System Infections, Machine Learning
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Dr. Jane Smith, MD, Neurocritical Care Physician, MD
[Source]“While high internal AUCs like 0.923 are promising, without external validation their applicability remains limited; models often over-perform in the derivation cohort.”
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Dr. Li Wei, PhD, Data Scientist & Neuroscience Researcher, PhD
[Source]“In many studies, predictive factors are selected via univariate analyses, but modern techniques like LASSO or embedded ML enhance feature selection and reduce bias.”
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Dr. Maria Gonzalez, MPH, Infectious Disease Epidemiologist, MPH
[Source]“Models that stratify risk can direct resources efficiently—targeting prophylactic measures to those most likely to benefit, while reducing unnecessary antibiotic use in low-risk patients.”
