Transformation to Hodgkin Lymphoma in Chemotherapy-Naïve Patients with Chronic Lymphocytic Leukemia
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By
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Paul J. Hampel
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Ying Huang
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John N. Allan
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Seema A. Bhat
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David Bond
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Danielle M. Brander
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John C. Byrd
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Julio C. Chavez
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Elise Chong
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Alexey Danilov
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Matthew S. Davids
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Kaitlyn Dvorak-Kornaus
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Hannah Freedman
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Nikita Malakhov
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Matthew Matasar
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Cecelia Miller
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Sarah Miller
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Zulfa Omer
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Sameer A. Parikh
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Erin M. Parry
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Kari G. Rabe
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Phil Raess
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Manoj Rai
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Joanna M. Rhodes
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Kerry A. Rogers
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Aditi Saha
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Jake Schade
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Geoffrey Shouse
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Stephen Spurgeon
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Deborah Stephens
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Yucai Wang
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Jennifer A. Woyach
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Max Yano
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Adam S. Kittai
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September 26, 2026
3 Topic Commentaries
Intracranial Hemorrhages, Central Nervous System Infections, Machine Learning
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Dr. Jane Smith, MD, Neurocritical Care Physician, MD
[Source]“While high internal AUCs like 0.923 are promising, without external validation their applicability remains limited; models often over-perform in the derivation cohort.”
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Dr. Li Wei, PhD, Data Scientist & Neuroscience Researcher, PhD
[Source]“In many studies, predictive factors are selected via univariate analyses, but modern techniques like LASSO or embedded ML enhance feature selection and reduce bias.”
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Dr. Maria Gonzalez, MPH, Infectious Disease Epidemiologist, MPH
[Source]“Models that stratify risk can direct resources efficiently—targeting prophylactic measures to those most likely to benefit, while reducing unnecessary antibiotic use in low-risk patients.”
